Adlay Testa (Coix lachryma-jobi L. var. Ma-yuen Stapf.) Ethanolic Extract and Its Active Components Exert Anti-Proliferative Effects on Endometrial Cancer Cells via Cell Cycle Arrest
Huang YJ, Chang CC, Wang YY, Chiang WC, Shih YH, Shieh TM, Wang KL, Ali M, Hsia SM · Molecules · 2021 March 31
DOI 10.3390/molecules26071966
Objective
To investigate the potential growth inhibitory effects of several adlay seed fractions, including ethyl acetate (ATE-EA) and its bioactive constituents, separately on endometrial cancer cells—HEC-1A (phosphatase and tensin homolog-positive) and RL95-2 (phosphatase and tensin homolog-negative)—and identify related active ingredients.
Conclusions
Our results demonstrate an antiproliferative effect of ethyl acetate (ATE-EA) on endometrial cancer cells that suggest a positive health outcome for women from consumption of these compounds.
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