A Multi-Target and Multi-Channel Mechanism of Action for Jiawei Yinhuo Tang in the Treatment of Social Communication Disorders in Autism: Network Pharmacology and Molecular Docking Studies
Linlin Z, Ciai L, Yanhong S, Huizhong G, Yongchun L, Zhen Y, Shan X, Fengying G, Ying L, Jingjun L, Qin F · Evidence-Based Complementary and Alternative Medicine · 2022 February 08
DOI 10.1155/2022/4093138
Objective
To identify the key targets, biological functions, and signal pathways of Jiawei Yinhuo Tang (JWYHT) in ASD social disorder (SCDA).
Conclusions
This study demonstrates that Jiawei Yinhuo Tang (JWYHT) regulates neuronal development, synaptic transmission, intestinal and cerebral inflammatory response, and other processes in ASD social disorder (SCDA).
Critical Appraisal
Published research can offer valuable insights, but a paper’s conclusions may go beyond what its results support. Critical appraisal examines the methods, findings and limitations to clarify what can reasonably be concluded—and what remains uncertain.
This article has not yet been critically appraised by the Research Hub.
Learn more about Critical Appraisal