Uncovering Synergistic Mechanism of Chinese Herbal Medicine in the Treatment of Atrial Fibrillation with Obstructive Sleep Apnea Hypopnea Syndrome by Network Pharmacology
Mao T, Zhang J, Qiao Y, Liu B, Zhang S · Evidence-Based Complementary and Alternative Medicine · 2019 December 24
DOI 10.1155/2019/8691608
Objective
This study applied network pharmacology to identify 94 active components in the six TCM liver-regulating herbs and 182 corresponding targets from several databases and comprehensive literature studies, as well as retrieved atrial fibrillation (AF) combined with obstructive sleep apnea hypopnea syndrome (OSAHS)-related targets.
Conclusions
This study demonstrates the multicomponent, multitarget, and multipathway feature of TCM liver-regulating herbs, provides an extensional foundation for further research, and facilitates the reasonable application of TCM liver-regulating herbs in treating paroxysmal AF combined with OSAHS.
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