The formulae and biologically active ingredients of Chinese herbal medicines for the treatment of atopic dermatitis
Yan F, Li F, Liu J, Ye S, Zhang Y, Jia J, Li H, Chen D, Mo X · Biomedicine & Pharmacotherapy · 2020 July
DOI 10.1016/j.biopha.2020.110142
Objective
This review focuses on TCM as well as its bioactive ingredients for the treatment of atopic dermatitis (AD), from the perspectives of animal model construction, pharmacodynamic mechanisms and clinical studies of formulae.
Conclusions
In this review we summarised multiple TCM bioactive herbal ingredients and formulae for the treatment of atopic dermatitis (AD) via oral or topical administration. Most TCMs exert anti-inflammatory, anti-allergic, anti-oxidative, and anti-angiogenic effects, which can attenuate AD through various mechanisms such as restoring skin barriers, balancing Th1/Th2 cells levels, as well as regulating cytokine and chemokine expression, with few side-effects.
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