Traditional Chinese Medicine when combined with vitamins significantly improves sperm characteristics and pregnancy rates in male infertility treatment.
The methodology used for this research involved a comprehensive review and meta-analysis of all relevant randomized controlled trials that utilized a combination of Traditional Chinese Medicine and vitamins for treating male infertility. These studies were sourced from a variety of databases including CNKI, Wanfang, VIP Database, CBM, MEDLINE, EMBASE, and the Cochrane Library. The quality of the chosen articles was assessed with the Cochrane Reviewer's Handbook 5.3, and meta-analysis was conducted using Stata 15 software.
The results indicate that compared to solely Vitamin E or Vitamin E and C, the incorporation of Traditional Chinese Medicine with vitamins led to considerable improvements in sperm concentration, motility, viability, liquefaction time, acrosome enzyme activity and in the overall pregnancy rate for male infertility cases. Certain specific Traditional Chinese Medicine capsules – Shengjing, Huanshao, and compound Xuanju – demonstrated particularly significant enhancements with respect to sperm concentration, sperm movement, and pregnancy rate. Consequently, the combination was found to have significant efficacy in treating male infertility without increasing side effects.