Acupuncture, particularly when used alongside antidepressants, can effectively alleviate various types of depression symptoms and reduce side effects of medication.
This review set out to summarize the available data regarding the mechanisms behind, and clinical efficacy of, acupuncture in treating depression, and to compare it with pharmacological interventions. The investigation analyzed studies conducted on animal models of depression and patients diagnosed with this disorder. These studies have indicated that acupuncture has the potential to promote neuroplasticity in the hippocampal region and other neural networks, and may mitigate brain inflammation, which could in turn reduce depressive symptoms.
The overall conclusions from clinical studies were that acupuncture could offer relief from symptoms in cases of primary depression, particularly milder ones. It has also been found to be beneficial in managing post-stroke depression, depression related to pain, and postpartum depression. Perspectives on the use of acupuncture alone and as a complimentary therapeutic approach were also considered in this review. The findings suggest that combining acupuncture with pharmacological antidepressant treatments can enhance symptom improvement and decrease the side effects of the drugs, which often contribute to high patient dropout rates in pharmaceutical-based treatments.