Anti-hypertensive and vasodilatory effects of amended Banxia Baizhu Tianma Tang
Tan CS, Loh YC, Ng CH, Ch’ng YS, Asmawi MZ, Ahmad M, Yam MF · Biomedicine & Pharmacotherapy · 2018 January
DOI 10.1016/j.biopha.2017.11.021
Objective
To investigate the possible mechanism of actions involved in the vasodilatory activity of amended Banxia Baizhu Tianma Tang-50 (ABBT-50) by evaluating its vasodilative effect on isolated Sprague Dawley rats in the presence of absence of various antagonists.
Conclusions
Vasodilatory effects of ABBT-50 are mediated through NO/sGC/cGMP cascade and PGI2, followed by muscarinic pathways and calcium channels.
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