Coix seed oil ameliorates cancer cachexia by counteracting muscle loss and fat lipolysis
Liu H, Li L, Zou J, Zhou T, Wang B, Sun H, Yu S · BMC Complementary Medicine and Therapies · 2019 October 15
DOI 10.1186/s12906-019-2684-4
Objective
Cancer cachexia is a cancer-induced multifactorial debilitating syndrome directly accounting for 20% of cancer deaths without effective therapeutic approaches. It is extremely urgent to explore effective anti-cachexia drugs to ameliorate muscle and fat loss in cachexia patients.
Conclusions
Coix seed oil exerts an anti-cachexia pharmaceutical effect by counteracting muscle and adipose tissue loss most likely through regulating NF-κB-MuRF1 and AMPK-HSL pathway.
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