Anti-osteoporosis effects and regulatory mechanism of Lindera aggregata based on network pharmacology and experimental validation

Wang F, Rong P, Wang J, Yu X, Wang N, Wang S, Xue Z, Chen J, Meng W, Peng X · Food & Function · 2022 January

Objective

To explore the active components and potential mechanisms of root of Lindera aggregata (RLA) in osteoporosis treatment.

Conclusions

Our results demonstrated the reliability of the network pharmacology method, and also revealed the anti-osteoporosis (OP) effect and potential mechanism of root of Lindera aggregata (RLA).

Critical Appraisal

Published research can offer valuable insights, but a paper’s conclusions may go beyond what its results support. Critical appraisal examines the methods, findings and limitations to clarify what can reasonably be concluded—and what remains uncertain.

This article has not yet been critically appraised by the Research Hub.

Learn more about Critical Appraisal