Proteomic Analysis of Human Follicular Fluid Reveals the Pharmacological Mechanisms of the Chinese Patent Drug Kunling Pill for Improving Diminished Ovarian Reserve
Wang H, Cao D, Wang M, Shi Y, Wei B, Jiang S, Jiang Y, Lian H, Xue X, Ma Z, Li J · Evidence-Based Complementary and Alternative Medicine · 2022 May 28
DOI 10.1155/2022/5929694
Objective
To explore the pharmacological mechanism of a Chinese patent drug (Kunling Pill (KLP)) on improving diminished ovarian reserve based on proteomic analysis.
Conclusions
Functional analyses of proteome datasets revealed that core proteins and related pathways are possible pharmacological mechanisms through which KLP improves DOR. Therefore, these findings may help better understand the complex mechanisms through which DOR is treated by the Chinese patent drug KLP.
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