Study on the mechanism of Yupingfeng powder in the treatment of immunosuppression based on UPLC⁃QTOF⁃MS, network pharmacology and molecular biology verification
Li Y, Liu Y, Sun Y, Ma S, Ma C, Zhou H, Chen G, Liu L, Cai D · Life Sciences · 2022 January
DOI 10.1016/j.lfs.2021.120211
Objective
The current study aims to investigate the effect of Yupingfeng (YPF) powder on immunosuppression, and explore the possible mechanisms.
Conclusions
The series of experiments demonstrate that YPF could improve Candida albicans induced immunosuppression of BALB/c mice through upregulating the activity of IL-17 pathway, suggesting that YPF might play an immunopotentiation effect and giving a clue that YPF may be used in treating Candida albicans.
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