Identification of the effective constituents for anti-inflammatory activity of Ju-Zhi-Jiang-Tang, an ancient traditional Chinese medicine formula
Wang S, Chen P, Jiang W, Wu L, Chen L, Fan X, Wang Y, Cheng Y · Journal of Chromatography A · 2014 June
DOI 10.1016/j.chroma.2014.04.084
Objective
To identify the effective constituents of Ju-Zhi-Jiang-Tang (JZJT) based on LC–MS techniques and pharmacological activity evaluation.
Conclusions
The results showed that two polymethoxy flavones with higher positive index values, i.e., nobiletin and tangeretin can significantly exert anti-inflammatory effects, while other compounds with negative values did not show any activity.
Critical Appraisal
Published research can offer valuable insights, but a paper’s conclusions may go beyond what its results support. Critical appraisal examines the methods, findings and limitations to clarify what can reasonably be concluded—and what remains uncertain.
This article has not yet been critically appraised by the Research Hub.
Learn more about Critical Appraisal