Aqueous extract of Paeoniae Radix Rubra prevents deep vein thrombosis by ameliorating inflammation through inhibiting GSK3β activity
Lu Z, Ye Y, Liu Y, Yang X, Ding Q, Wang Y, Wu Z, Zhan Y, Gui S, Lin B, Lin B · Phytomedicine · 2021 November
DOI 10.1016/j.phymed.2021.153767
Objective
To assess the potential inhibitory effect of the aqueous extract of Paeoniae Radix Rubra (PRR) (i.e.,PRR dispensing granule, PRRDG) on deep vein thrombosis (DVT) and explore the underlying mechanism.
Conclusions
Paeoniae Radix Rubra dispensing granule (PRRDG) prevents deep vein thrombosis (DVT) by ameliorating inflammation through inhibiting GSK3β activity.
Critical Appraisal
Published research can offer valuable insights, but a paper’s conclusions may go beyond what its results support. Critical appraisal examines the methods, findings and limitations to clarify what can reasonably be concluded—and what remains uncertain.
This article has not yet been critically appraised by the Research Hub.
Learn more about Critical Appraisal