Common Beans and Their Non-Digestible Fraction: Cancer Inhibitory Activity—An Overview
Campos-Vega R, Oomah B, Loarca-Piña G, Vergara-Castañeda H · Foods · 2013 August 02
DOI 10.3390/foods2030374
Objective
To investigate the potential health benefits and bioactivity of beans on tumor inhibition, highlighting studies involving functional compounds, mainly non-digestible fractions that modulate genes and proteins, thereby, unraveling their preventive role against the development of cancer.
Conclusions
Dietary modification by increasing the daily consumption of a wide variety of common beans is a practical strategy for consumers to optimize their health and reduce the risk of cancer. Beans are good sources of bioactive compounds and recent evidence provides information of their impact and mechanism of action on this pathology, mainly for non-digestible fraction of beans on colon cancer. This effect seems to be related mainly to cell proliferation, cell cycle, apoptosis, cell invasion and histone modulation.
Critical Appraisal
Published research can offer valuable insights, but a paper’s conclusions may go beyond what its results support. Critical appraisal examines the methods, findings and limitations to clarify what can reasonably be concluded—and what remains uncertain.
This article has not yet been critically appraised by the Research Hub.
Learn more about Critical Appraisal
