Feasibility and Acceptability of a Healthy Nordic Diet Intervention for the Treatment of Depression: A Randomized Controlled Pilot Trial
Sabet JA, Ekman MS, Lundvall AS, Risérus U, Johansson U, Öström , Adamsson V, Cao Y, Msghina M, Brummer RJ · Nutrients · 2021 March 10
DOI 10.3390/nu13030902
Objective
To test the palatability of the meals and the acceptability of the intervention in preparation for an 8-week RCT in the future, which will investigate whether a healthy Nordic diet improves depressive symptoms in individuals with major depressive disorder, and associated biological mechanisms.
Conclusions
This pilot study demonstrates the feasibility and acceptability of an RCT comparing a healthy Nordic diet with a control diet in individuals with depression, in which all meals are provided to both groups. This study lays the foundation for a future 8-week RCT in which the aim will be to investigate whether a healthy Nordic diet improves depressive symptoms, as well as the biological mechanisms underlying this effect and potential factors that may predict treatment response.
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