Pomegranate consumption can effectively manage rheumatoid arthritis complications by reducing inflammation and oxidative stress without adverse effects.
The methodology involved in this review systematically examined available evidence related to pomegranate's impact on rheumatoid arthritis (RA). This study involved an extensive search of electronic databases such as PubMed, WOS, Cochrane Library, Scopus, Embase, and Google Scholar until March 2020, alongside search alert services for recent publications. Included were relevant clinical, animal, and in vitro studies, while review papers, conference abstracts, book chapters, or articles considering the effects of pomegranate in combination with other plants or its effects on other illnesses were excluded.
The results pointed towards the beneficial effects of pomegranate. It was observed across human, animal, and in vitro studies that pomegranate significantly impacted clinical symptoms, inflammatory and oxidative factors in RA patients. Further, it was found that pomegranate helped manage RA complications by mitigating the inflammation and oxidative stress involved, and no severe unfavorable results were reported concerning pomegranate consumption.
