Ginger and Testosterone

Banihani SA · Biomolecules · 2018 October 22

Objective

To discuss and summarize the effect of ginger and ginger extracts on testosterone.

Conclusions

In conclusion, the mainstream of research that links ginger to testosterone demonstrated that ginger supplementation, particularly in oxidative stress conditions, enhances testosterone production in males.

Critical Appraisal

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Insights

Ginger supplementation enhances the production of testosterone in males by reducing oxidative stress and increasing luteinizing hormone production, cholesterol in testes, and blood flow to the testes.

The study reviewed a collection of English language articles from three databases— PubMed, Scopus, and Web of Science— from November 1991 through August 2018. Keywords for the search included "ginger" and "testosterone". The references from relevant published articles were also reviewed. The methodology encompassed both in-vivo and basic research studies that sought to discover a link between ginger and testosterone. The results revealed that ginger supplementation enhances testosterone production in males, particularly in conditions of oxidative stress. This effect is achieved primarily by increasing the production of luteinizing hormone, cholesterol levels in the testes, reducing testes oxidative stress and lipid peroxidation, enhancing antioxidant enzyme activity, normalizing blood glucose and increasing blood flow in the testes. Furthermore, the study shows a correlation between ginger supplementation and increased testicular weight, and recycling of testosterone receptors.