Honey and obesity-related dysfunctions: a summary on health benefits

Terzo S, Mulè F, Amato A · The Journal of Nutritional Biochemistry · 2020 August

DOI 10.1016/j.jnutbio.2020.108401

Objective

To review the potential therapeutic benefits of honey, containing flavonoids and phenolic acids, particularly focusing on its antioxidant and anti-inflammatory properties, in the management of chronic diseases associated with oxidative stress and inflammation, with a specific emphasis on obesity-related dysfunctions, including neurodegeneration.

Conclusions

Experimental evidence from animal studies suggests that honey, administered alone or in combination with conventional therapy, may be useful in managing chronic diseases like obesity, characterized by oxidative stress and inflammation. Honey has shown to improve glycemic control and lipid profiles, offering protection from endothelial dysfunction and neurodegeneration. Polyphenols present in honey are highlighted as potential key constituents responsible for these health benefits. However, further well-designed and controlled studies in humans are needed to validate these findings.

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Insights

Honey, with its variable composition based on botanical origin, exhibits antioxidant and anti-inflammatory properties, suggesting its potential efficacy in managing obesity-related dysfunctions, including neurodegeneration, through improved glycemic control and lipid profile.

The review explores honey's therapeutic potential, emphasizing its diverse bioactive compounds. The focus is on its effects in combating obesity-related dysfunctions, supported by experimental evidence from animal studies. Experimental findings indicate that honey can enhance glycemic control and lipid profile, offering protection against endothelial dysfunction and neurodegeneration in obesity. The role of honey's key constituents, particularly polyphenols, is highlighted, underscoring the need for further human studies to confirm these health benefits.