Effects of Flavonoid Supplementation on Common Eye Disorders: A Systematic Review and Meta-Analysis of Clinical Trials
Davinelli S, Ali S, Scapagnini G, Costagliola C · Frontiers in Nutrition · 2021 May 25
DOI 10.3389/fnut.2021.651441
Objective
The systematic review and meta-analysis aim to assess the effect of dietary flavonoids on major eye disorders.
Conclusions
The pooled results, based on 11 intervention trials involving 724 participants, suggest an overall significant effect of flavonoids on common ophthalmic disorders. Flavan-3-ols and anthocyanins are identified as effective interventions for improving outcomes in ocular conditions. However, evidence on the efficacy of several other flavonoid subclasses is deemed insufficient. The study concludes that while flavonoids may improve clinical manifestations associated with ocular disorders, further well-constructed clinical trials are needed to confirm these findings and explore the effects of flavonoids on other eye disorders.
Critical Appraisal
Published research can offer valuable insights, but a paper’s conclusions may go beyond what its results support. Critical appraisal examines the methods, findings and limitations to clarify what can reasonably be concluded—and what remains uncertain.
This article has not yet been critically appraised by the Research Hub.
Learn more about Critical Appraisal
