Mineral Water Vincentka and its Influence on Mucosal Ulcers

BUDINSKAYA K, NÁDENÍČEK J, STRAČINA T, HENDRYCH M, PÍREK O, BARTÁKOVÁ A, ŠUDÁKOVÁ M, SVÍZELA V, NOVÁKOVÁ Z, NOVÁKOVÁ M, BABULA P · Physiological Research · 2022 December 30

DOI 10.33549/physiolres.935013

Objective

To investigate the effects of drinking Vincentka natural mineral water on the symptoms and development of acute gastric ulcers in an animal model.

Conclusions

The study concludes that drinking Vincentka mineral water has a positive impact on the development and symptoms of acute gastric ulcers.

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Insights

Vincentka natural mineral water reduces gastric damage and improves antioxidant capacity in an animal model of acute gastric ulcers.

This pilot study involved 16 male Wistar rats, divided into two groups: an experimental group and a control group, each with eight rats. The study was conducted in three phases: a 7-day handling phase, a 7-day phase where the experimental group received Vincentka mineral water and the control group received tap water, and a final phase of acute gastritis induction lasting one day. After 24 hours post-induction, the animals were sacrificed for analysis. Tissue samples from the stomach and duodenum, as well as blood samples, were examined using histological microscopy, immunohistochemical, and biochemical methods. The histopathological analysis showed significantly less damage to the stomach lining in the experimental group compared to the control group. There were notable differences in blood plasma antioxidant capacity, oxidative stress parameters, and other biochemical values between the groups. These findings indicate that Vincentka mineral water positively affects the development and symptoms of acute gastric ulcers in this animal model, suggesting potential benefits for similar human conditions.