Hépar mineral water, rich in sulphates and magnesium, effectively treats functional constipation, showing significant results within 7 days.
In this multicenter, randomized, double-blind, controlled study, 226 outpatients with functional constipation were evaluated. Participants underwent a washout period before consuming 1.5 liters of water daily for 14 days, of which 1 liter was either Hépar or low-mineral water. Patients self-reported stool consistency daily, and an expert investigator, blinded to the treatment groups, evaluated stool consistency using the Bristol stool scale based on patient-provided photographs.
The study successfully met its primary endpoint, with 50% of participants in the Hépar group responding to treatment by day 14, compared to 29% in the control group. The average time to observe a treatment response was 6.4 days for Hépar users, shorter than the 7.3 days in the control group. Approximately 60% of patients provided stool scores, with 79% of these scores closely aligning between patients and experts. The safety analysis of Hépar indicated excellent results, confirming its efficacy and safety in treating functional constipation.
