High consumption of carrots is associated with a reduced risk of urothelial cancer.
The methodology for this meta-analysis comprised of a comprehensive search across databases like PubMed, Web of Science, Scopus, EMBASE, Cochrane register, and Chinese National Knowledge Infrastructure. Studies up till January 2017 regarding the correlation between carrot intake and urothelial cancer risk were evaluated. The selected studies included four case-control studies and two cohort studies, six in total. The combined odds ratio for the highest versus the lowest intake of carrot was computed to measure risk correlation.
The results showed a notable reduction in the risk of urothelial cancer for individuals with high intake of carrots. However, significant heterogeneity was observed among the included studies. Additionally, there was no substantial publication bias found by applying both Begg's test and Egger's test. Even in the light of the observed heterogeneity and limited studies, the key conclusion points towards high carrot intake as a potential contributor to lower urothelial cancer incidence.
