Zinc oxide-induced changes to sunscreen ingredient efficacy and toxicity under UV irradiation
Ginzburg AL, Blackburn RS, Santillan C, Truong L, Tanguay RL, Hutchison JE · Photochemical & Photobiological Sciences · 2021 October
DOI 10.1007/s43630-021-00101-2
Objective
To investigate the influence of sunscreen formulation on photostability and toxicity by evaluating the effects of zinc oxide additives on small-molecule based ultraviolet-filter mixtures.
Conclusions
The presence of zinc oxide in sunscreens containing small-molecule UV-filters leads to significant photodegradation of the mixture and increased toxicity, indicating the need for caution when formulating such sunscreens.
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