Mao Xu Cao has shown potential in treating diabetes and its complications by influencing metabolic processes and displaying antioxidant and anti-inflammatory properties.
The study adopted the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) methodology. Extensive literature search was conducted using the databases ScienceDirect, PubMed, and Web of Science. All chosen articles were thoroughly assessed to understand the effects of Benth. on diabetes and its complications.
In terms of results, it was found that the primary mechanisms through which Benth. contributes to the treatment of diabetes and its complications include inhibition of α-amylase and α-glucosidase activities, enhanced antioxidant and anti-inflammatory activities, regulation of lipid metabolism, stimulation of insulin secretion, improvement of insulin resistance, and promotion of glucose uptake among other positive effects. The hypoglycemic effects of Benth. are potentially due to the presence of phenolic acids, flavonoids, and triterpenoids. This suggests the potential of Benth. as an antidiabetic agent.