The clinical impact of an extra virgin olive oil enriched mediterranean diet on metabolic syndrome: Lights and shadows of a nutraceutical approach
Seidita A, Soresi M, Giannitrapani L, Di Stefano V, Citarrella R, Mirarchi L, Cusimano A, Augello G, Carroccio A, Iovanna JL, Cervello M · Frontiers in Nutrition · 2022 August 04
DOI 10.3389/fnut.2022.980429
Objective
To investigate and review the clinical properties of extra virgin olive oil (EVOO), especially its potential as a therapeutic component in the treatment of metabolic syndrome (MS) and related complications, such as cardiovascular diseases, diabetes mellitus, steatosis, and non-alcoholic steatohepatitis.
Conclusions
The study concludes that the Mediterranean diet (MD) enriched with extra virgin olive oil (EVOO) offers potential health benefits, including antioxidant, anti-inflammatory, insulin-sensitizing, cardioprotective, antiatherogenic, neuroprotective, immunomodulatory, and anticancer activities. However, the authors emphasize the need for further research to fully understand the clinical efficacy and the underlying biochemical and molecular mechanisms of EVOO in treating metabolic syndrome and its associated complications.
Critical Appraisal
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