Green tea extract can potentially control pain and improve knee joint physical function in adults suffering from osteoarthritis.
The study employed a randomized open-label active-controlled clinical trial in which fifty adults with knee osteoarthritis were randomly divided into two groups. One group received the green tea extract in tablet form along with diclofenac tablet, referred to as the "intervention group," while the other, the "control group," received only the diclofenac tablet. This trial period lasted four weeks. The researchers evaluated the patients at the start of the trial and then four weeks later, measuring the pain score through a visual analogue scale and a specific osteoarthritis questionnaire's score, in addition to its three sub-scores. The participants were also asked to report any side effects experienced during the trial period.
The outcomes of the experiment showed that when compared to the control group, the green tea group showed a significant decrease in their pain score and the score measuring knee joint function. However, no differences were observed between the two groups in terms of the specific osteoarthritis questionnaire's pain and stiffness scores. An adverse event of gastric upset was reported in only one patient from the control group.