Urinary Phenolic Metabolites Associated with Peanut Consumption May Have a Beneficial Impact on Vascular Health Biomarkers
Parilli-Moser I, Domínguez-López I, Vallverdú-Queralt A, Hurtado-Barroso S, Lamuela-Raventós R · Antioxidants · 2023 March 11
DOI 10.3390/antiox12030698
Objective
The aim of this study was to assess the association of urinary phenolic metabolites (UPMs) with vascular biomarkers following the consumption of skin roasted peanuts (SRP) and peanut butter (PB) in a randomized controlled trial with a control group.
Conclusions
Consumers of SRP and PB exhibited significantly higher excretion of specific UPMs, including enterodiol glucuronide, 3-hydroxybenzoic acid, vanillic acid sulfate, p-coumaric acid, coumaric acid glucuronide I and II, and isoferulic acid, compared to the control group. The peanut interventions also led to an improvement in prostacyclin I2 (PGI2) levels and the thromboxane A2 (TXA2):PGI2 ratio. Higher post-intervention levels of UPMs were correlated with positive changes in vascular biomarkers, indicating a potential positive impact of peanut product consumption on vascular health.
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