The extract from cucumber, Q-Actin, is effective in reducing moderate knee osteoarthritis related pain and potentially in managing knee pain, stiffness, and physical functions.
In this double-blind, parallel-group clinical trial conducted in three different centres, 122 patients aged between 40 and 75 years with diagnosed moderate knee Osteoarthritis were randomly divided into two groups. Over a 180-day period, one group received the cosmetically prescribed dose of 1,350 mg of glucosamine-chondroitin orally twice daily, and the other group took an orally administered 10 mg of Q-Actin (aqueous extract of cucumber) twice per day.
The results showed a significant decrease in Osteoarthritis Index scores in the group that received the cucumber extract, indicating reduced pain and improved physical function. This trend was observed throughout the trial, and by the 180th day, the extract's effectiveness was substantially higher than that of the traditionally prescribed glucosamine-chondroitin. Notably, no adverse effects from the cucumber extract were reported during the trial period.
