Anti-inflammatory and Antioxidant Activity of Cucumis sativus and Citrus macroptera Herbal Formulation: An In-Vitro Study

Amani T, Surenthar M, Shanmugam R · Cureus Journal of Medical Science · 2024 January 07

Objective

To evaluate the antioxidant and anti-inflammatory activity of a formulation comprising Cucumis sativus, Citrus macroptera, and glycerol extract as a potential alternative to synthetic drugs for treating oral disorders.

Conclusions

The combination of cucumber, citrus, and glycerol extract demonstrated significant antioxidant and anti-inflammatory properties, comparable to standard values, as indicated by assays such as 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging, Hydrogen Peroxide (H2O2), Bovine serum albumin (BSA), and Egg albumin (EA) denaturation assays. The extracts showed appreciable effects at concentrations of 30, 40, and 50 µl, with the maximum concentration of 50 µl exhibiting optimal antioxidant and anti-inflammatory activity.

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