Acupuncture for chemotherapy-associated insomnia in breast cancer patients: an assessor-participant blinded, randomized, sham-controlled trial
Zhang J, Qin Z, So TH, Chang TY, Yang S, Chen H, Yeung WF, Chung KF, Chan PY, Huang Y, Xu S, Chiang CY, Lao L, Zhang ZJ · Breast Cancer Research · 2023 April 26
DOI 10.1186/s13058-023-01645-0
Objective
To determine the efficacy and safety of acupuncture in improving chemotherapy-associated insomnia in breast cancer patients.
Conclusions
The active acupuncture regimen, combining needling into body acupoints and acupressure on auricular acupoints, was not superior to sham control in reducing the Insomnia Severity Index (ISI) score from baseline to 6 weeks. However, it produced short-term treatment and long-term follow-up better outcomes in improving sleep onset latency, total sleep time, sleep efficiency, anxiety, depression, and quality of life. Participants in the active acupuncture group had a higher cessation rate of sleeping medications than the sham control, indicating that acupuncture could be an effective option for managing chemotherapy-associated insomnia and serve as a tapering approach to reduce the use of sleeping medications in breast cancer patients.
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