Pomegranate juice can reduce melatonin, increase insulin levels, and improve insulin resistance in individuals with impaired fasting glucose.
This study was a randomized clinical trial with 28 participants who had been diagnosed with impaired fasting glucose. They were selected from Irbid Central Laboratory and the Diabetes Clinic of the University Hospital at Jordan University of Science and Technology. Each participant received a dose of fresh pomegranate juice calculated at 1.5 ml per kilogram of their body weight. Blood samples for each participant were taken prior to, 1 hour and 3 hours after ingesting the juice. The studied parameters were melatonin, insulin, and glucose levels.
In terms of results, it was found that people with impaired fasting glucose, contrary to those who were healthy, showed a significant decrease in blood glucose levels 3 hours after consuming the juice. Insulin resistance also improved significantly within the same time frame for these individuals. Furthermore, melatonin levels decreased, and insulin levels increased noticeably among both, healthy as well as those with impaired fasting glucose, an hour after the juice intake. These results suggest that fresh pomegranate juice can positively affect hormones related to diabetes and sleep.