Effect of oral L-citrulline on brachial and aortic blood pressure defined by resting status: evidence from randomized controlled trials
Yang HH, Li XL, Zhang WG, Figueroa A, Chen LH, Qin LQ · Nutrition & Metabolism · 2019 December 26
DOI 10.1186/s12986-019-0415-y
Objective
This study aims to summarize the clinical evidence regarding the effects of L-Cit supplementation on brachial systolic blood pressure (SBP), brachial diastolic blood pressure (DBP), in addition to aortic SBP and aortic DBP at rest and non-resting conditions.
Conclusions
L-Cit supplementation significantly decreased non-resting brachial and aortic SBP. Brachial DBP was significantly lowered by L-Cit regardless of resting status
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Insights
L-citrulline supplementation significantly decreased non-resting brachial and aortic systolic blood pressure.
L-citrulline supplementation significantly decreased non-resting brachial and aortic systolic blood pressure. Brachial diastolic blood pressure was significantly lowered by L-citrulline regardless of resting status. Given the relatively small number of available trials in the stratified analyses and the potential limitations of these trials, the present findings should be interpreted cautiously and need to be confirmed in future well-designed trials with a larger sample size.
