Chinese herbal medicine as adjuvant therapy exerted an additive anti-vascular dementia benefit on Mini-Mental State Examination (MMSE) scores.
Meta-analysis showed that Chinese herbal medicine (CMH) for vascular dementia could improve Mini-Mental State Examination (MMSE), the Activities of Daily Living, Hasegawa’s dementia scale, and clinical effective rate but had statistically similar effect based on Blessed Behavior Scale (BBS) outcome when compared with WCTs. When compared with placebo, CHMs were more beneficial in improving MMSE but showed no significant difference in BBS scores. CHM as adjuvant therapy exerted an additive anti-vascular dementia benefit on MMSE scores. The participants of CHM group had fewer adverse events than that of the placebo group or WCT group.
The findings of the present study support, at least to an extent, that CHM can be recommended for routine use for treatment of vascular dementia.