The RUTI trial: A feasibility study exploring Chinese herbal medicine for the treatment of recurrent urinary tract infections
Flower A, Harman K, Willcox M, Stuart B, Moore M · Journal of Ethnopharmacology · 2019 October 28
DOI 10.1016/j.jep.2019.111935
Objective
To evaluate the feasibility of administering standardised and individualised formulations of CHM for RUTIs as a Clinical Trial of an Investigational Medicinal Product (CTIMP) within primary care of the UKs National Health Service (NHS).
Conclusions
The RUTI trial demonstrated the feasibility and challenges of conducting a CTIMP trial on Chinese herbal medicine, establishing regulatory pathways, identifying difficulties with trial-naive herbal suppliers and unfamiliar recruiters and participants, and suggesting that recruiting patients through self-help networks and private TCM clinics would be a promising approach for future trials.
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