Sepsis

Presentation Slides

Chinese Medicine Research Hub

Review Article

Acupuncture, via nerve stimulation, can be a promising treatment strategy for controlling inflammation and improving organ function during sepsis by activating immune reflexes.

2021 Autonomic Neuroscience: Basic and Clinical Acupuncture modulates immunity in sepsis: Toward a science-based protocol
Pan WX, Fan AY, Chen S, Alemi SF.

Chinese Medicine Research Hub

Systematic Review

Acupuncture at Zusanli (ST36) might be effective in reducing injuries induced by sepsis in various organs by reducing oxidative stress and inflammation.

2020 Evidence-Based Complementary and Alternative Medicine Acupuncture at Zusanli (ST36) for Experimental Sepsis: A Systematic Review
Lai F, Ren Y, Lai C, Chen R, Yin X, Tan C, Li J, Yang C, Liang G, Li J, Zeng R

Executive Summary

Write an executive summary in the form of a blog article on the topic of "Research into Chinese medicine treatment for Sepsis" summarising the research below and using language that can be easily understood by patients and avoiding medical jargon using a professional and caring tone of voice.

Write an executive summary in the form of a blog article on the topic of "Researched Chinese medicine treatments for Sepsis" summarising the research below in an objective and easy to understand way, and using language that can be easily understood by patients. Group the article into Chinese medicine treatments first, followed by nutrition and other treatments. Avoid using medical jargon and use a professional and caring tone of voice.

Write me a concise but easy to understand executive summary on the topic of "Chinese medicine treatments for Sepsis" based on the following research that I will give you. Your summary should be 2 paragraphs long in Australian English spelling and include references to the studies.

A Review Article published in 2021 in the journal Autonomic Neuroscience: Basic and Clinical found that Acupuncture, via nerve stimulation, can be a promising treatment strategy for controlling inflammation and improving organ function during sepsis by activating immune reflexes. The study used a neuromodulation approach, leveraging the technique of peripheral nerve stimulation through acupuncture. This was linked with known somatic-autonomous-immune reflexes with the aim to control inflammation and improve organ functions in sepsis cases. The local and systematic effects of this methodology were largely achieved through the activation of several reflexes. These included the somatic-sympathetic-splenic reflex, the somatic-sympathic-adrenal reflex, the somatic-vagal-splenic reflex, and the somatic-vagal-adrenal reflex. The activation of these particular reflexes is what sets acupuncture apart from other nerve stimulation techniques. In terms of results, the method used for immunomodulation and inflammation control showed considerable promise for sepsis treatment. The acupuncture procedure achieved regulation by activating appropriate reflexes which in turn produced a systemic effect, thereby controlling inflammation and enhancing organ function. The research findings underscore acupuncture as an effective therapy, providing significant advantages for immunomodulation in acute inflammation such as sepsis, leading to a comprehensive, evidence-based therapy recommendation.

A Systematic Review published in 2020 in the journal Evidence-Based Complementary and Alternative Medicine found that Acupuncture at Zusanli (ST36) might be effective in reducing injuries induced by sepsis in various organs by reducing oxidative stress and inflammation. The researchers conducted a systematic review of seven databases, covering the inception of each to May 2019. They identified 54 studies that used acupuncture at ST36, a specific acupuncture point, for treating experimental sepsis, drawing from both English and Chinese literature resources. The studies reviewed suggest that acupuncture could serve as a complementary strategy in treating sepsis by reducing damage in multiple body systems: cardiac, lung, kidney, liver, gastrointestinal tract, and the immune system. It's thought to achieve these results through several mechanisms: limiting oxidative stress, managing inflammation, improving microcirculation, and upholding immune balance with the help of dopamine. Worth noting, however, is that these positive findings must be carefully considered due to the methodological quality and potential publication bias of the included studies.

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