Shao Yao Gan Cao Tang

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Chinese Medicine Research Hub

Meta-Analysis

The traditional Chinese herbal medicine Shaoyao Gancao Tang (SG-Tang) may be an effective and safe alternative treatment to relieve Restless Leg Syndrome.

2023 Quality Assurance and Safety of Crops & Foods Efficacy and safety of Shaoyao Gancao Tang for restless leg syndrome: A systematic review and meta-analysis
Tian Z, Li R, Wei J, Huai W, Xia J, Jiang H, Xiong Y, Chen Y

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A Meta-Analysis published in 2023 in the journal Quality Assurance and Safety of Crops & Foods found that The traditional Chinese herbal medicine Shaoyao Gancao Tang (SG-Tang) may be an effective and safe alternative treatment to relieve Restless Leg Syndrome. The methodology used for this study involved a systematic review and meta-analysis of Randomized Clinical Trials (RCTs) assessing the efficacy and safety of SG-Tang treatment for Restless Leg Syndrome. Databases such as the Cochrane Library, PubMed, EMBASE, Web of Science, Chinese Biological Medicine Database, China National Knowledge Infrastructure, Wanfang Database, and VIP Information Database were searched. The primary and secondary outcome measurements looked at were the total effective rate, the International Restless Legs Syndrome Study Group Rating Scale for Severity of Restless Legs Syndrome, the Pittsburgh Sleep Quality Index, and the incidence of adverse events. The results of the study indicated that SG-Tang treatment led to significant improvements compared to conventional medications; it increased the total effective rate and lifted scores on the Severity of Restless Legs Syndrome and Sleep Quality Indices, while also lessening the incidence of adverse events. However, these conclusions should be interpreted with caution due to the limited data and the methodological quality of the included studies.

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