The herbal formula Modified Bu Zhong Yi Qi Tang significantly improves functional constipation symptoms with fewer adverse events.
Method: Extensive research was conducted on the formula Modified Buzhong-Yiqi-Tang (MBYT) used for adult patients suffering from functional constipation. Twenty-five randomized controlled clinical trials were selected and undertaken in accordance with predefined criteria. A total of 2089 patients' symptoms and responses to treatment were evaluated and compared against the effects of stimulant laxatives, osmotic laxatives, and prokinetic agents. The study also evaluated MBYT's efficacy as an adjuvant therapy.
Discussion of Results: The research found that MBYT treatment made significant improvements to patients' constipation symptoms when compared to other treatments. As an adjuvant therapy, it showed superior results in comparison to osmotic laxatives alone, prokinetic agents alone, and biofeedback alone. The review indicates a lesser number of adverse events for patients using MBYT compared to those in control groups. Despite the limited quality and scope of the trials, MBYT showed a remarkable therapeutic effect on adult patients with functional constipation.
