Medicine–food herb: Angelica sinensis, a potential therapeutic hope for Alzheimer's disease and related complications
Long Y, Li D, Yu S, Shi A, Deng J, Wen J, Li X, Ma Y, Zhang Y, Liu S, Wan J, Li N, Yang M, Han L · Food & Function · 2022 January
DOI 10.1039/D2FO01287A
Objective
Traditionally, the herb of Angelica sinensis (AS) comes from the root of an umbrella plant Angelica sinensis (Oliv.) Diels. As a typical medicine–food herb, studies have shown that AS can alleviate AD and AD-complications by multiple targets through the various foundations of pharmaceutical material and dietary supply basis. Therefore, this review summarizes the pharmacological effects of AS for the treatment of AD and AD-complications for the first time.
Conclusions
The role of dietary supplement components in AS for AD intervention is summarized, including vitamin B12, folic acid, arginine, and oleic acid, which can improve the symptoms of AD. Besides, this review focuses on the safety and toxicity evaluation of AS, which provides a basis for its application. This review will provide further support for the research on AD and the application of medicine–food herb AS in a healthy lifestyle in the future.
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