Botany, traditional uses, phytochemistry, analytical methods, processing, pharmacology and pharmacokinetics of Bupleuri Radix: A systematic review
Jiang H, Yang L, Hou A, Zhang J, Wang S, Man W, Zheng S, Yu H, Wang X, Yang B, Wang Q, Kuang H · Biomedicine & Pharmacotherapy · 2020 November
DOI 10.1016/j.biopha.2020.110679
Objective
Bupleuri Radix (BR) is the dry root of Bupleurum chinense DC. and Bupleurum scorzonerifolium Willd. It has the functions of evacuation and antipyretic, soothing liver and relieving depression and often used to treat cold fever, chest and rib swelling pain, irregular menstruation, uterine prolapse, rectocele and other diseases. In this paper, the botany, traditional application, phytochemistry, pharmacology and toxicity of BR were reviewed.
Conclusions
Compared with the previous review of BR, this review is the most comprehensive, latest and in-depth summary of BR. This paper not only summarizes the studies of botany, traditional applications, phytochemistry, pharmacology, and toxicity. It is also the first time to summarize and analyze the analysis method, quality control, processing method, processing action and pharmacokinetics of BR based on the limited literature.
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