Evaluating the Therapeutic Efficacy of Si-Wu-Tang Decoction and Concentrated Extract in Follicular Maldevelopment-Related Menstrual Disorders Through Pharmacokinetic/Pharmacodynamic Studies
Lee CJ, Kapelemera AM, Tsai YZ, Lee CT, Xu MY, Wang CC · Frontiers in Pharmacology · 2020 September 04
DOI https://doi.org/10.3389/fphar.2020.01245
Objective
To produce Chinese herbal extracts (CHEs) and a decoction of Si-Wu-Tang (SWT) aiming to explore the bioequivalence of the two formulations through pharmacokinetic (PK) and pharmacodynamic (PD) studies on healthy volunteers and provide reference for future clinical use.
Conclusions
In conclusion, Si-Wu-Tang could improve ovarian follicular maldevelopment.
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