Effects of Canola Oil Consumption on Lipid Profile: A Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials
Ghobadi S, Hassanzadeh-Rostami Z, Mohammadian F, Zare M, Faghih S · Journal of the American College of Nutrition · 2018 October 31
DOI 10.1080/07315724.2018.1475270
Objective
To quantify the effects of canola oil (CO) consumption on lipid parameters, including total cholesterol (TC), low-density lipoprotein cholesterol (LDL), high-density lipoprotein cholesterol (HDL), triglycerides (TG), apolipoprotein A1 (Apo A1), and apolipoprotein B (Apo B), through a systematic review and meta-analysis of randomized controlled trials.
Conclusions
Canola oil (CO) consumption significantly reduced TC and LDL, with no significant effects on HDL, TG, Apo B, and Apo A1. Subgroup analyses indicated that the effects on TC and LDL were more pronounced in participants over 50 years of age and with an intervention duration of over 30 days. Additionally, CO showed a greater reduction in LDL and TC compared to sunflower oil and saturated fat. The meta-analysis suggests that CO consumption improves serum TC and LDL, potentially delaying the progression of heart disease.
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