Conclusions
In rats with acetic acid-induced ulcerative colitis, the administration of virgin coconut oil demonstrated a significant improvement in final weight, weight gain, feed efficiency ratio, stomach organ weight, antioxidant enzymes (CAT, SOD, GSH, GSR, GPx, GST), and a significant reduction in oxidative stress markers (MDA, H2O2), inflammatory markers (CRP, IL-6, PG2), compared to the control group. These findings suggest that virgin coconut oil has a potential curative effect on acetic acid-induced ulcerative colitis in rats, emphasizing its potential as a therapeutic agent in the management of ulcerative colitis.
