Beneficial Effects of Young Coconut Juice on Increasing Skin Thickness, Enhancing Skin Whitening, and Reducing Skin Wrinkles in Ovariectomized Rats
Radenahmad N, Sereemaspun A, Bueraheng N, Hutapea AM · Applied Sciences · 2022 February 01
DOI 10.3390/app12031584
Objective
To optimize the dosage of young coconut juice for improving wound healing and skin complexion in ovariectomized rats, considering the unfavorable side effects observed at 100 mL/kg BW/day.
Conclusions
Young coconut juice at lower doses (10, 20, and 40 mL/kg BW/day) was found to effectively restore skin changes in ovariectomized rats, including epidermal and dermal thickness, hair follicle number, collagen fibril diameters, perimeters, and nuclei of fibroblast and keratinocyte cells. The ultrastructural changes in keratinocyte and fibroblast cells were also significantly reduced, with the optimal dose identified as 40 mL/kg BW/day. The study suggests that young coconut juice may be as effective as estradiol benzoate in reducing skin atrophy/aging, possibly acting as a selective estrogen receptor moderator.
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