Morinda citrifolia fruit extract effectively supports bone regeneration and has anti-inflammatory properties in periodontal bone defects.
This study randomized twenty patients who required periodontal regenerative therapy into two groups - an experimental group and a control group. For the control group, open flap debridement alone was used while in the experimental group, the application of Morinda citrifolia fruit extract was coupled with open flap debridement. Clinical aspects such as the gingival index, probing depth of pockets, and relative attachment level were assessed, along with the quantity of bone fill using cone-beam computed tomography at the beginning and after six months.
The use of Morinda citrifolia fruit extract in the experimental group resulted in a significant reduction in probing pocket depth and increase in relative attachment level. Furthermore, the extract promoted a higher rate of bone fill in the experimental group compared with the control group, suggesting efficiency in the treatment of intraosseous defects. Additionally, the extract showcased some anti-inflammatory effects, amplifying its potential therapeutic uses.
