Cinnamon supplementation significantly reduces blood triglycerides and total cholesterol levels without affecting low-density and high-density lipoprotein cholesterol.
The study's methodology included the systematic review and evaluation of 13 randomized controlled trials involving 750 participants. These trials examined the impact of cinnamon supplementation on blood lipid concentrations. The researchers performed a meta-analysis employing random effect models and calculated weighted mean differences for endpoints using a random effects model too.
The results of the study indicated no substantial effect of cinnamon on low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (HDL-C) concentrations. However, a significant decrease in blood triglycerides and total cholesterol concentrations was observed. Furthermore, in a meta-regression analysis, no notable association was found between changes in lipid parameters and the dosage of cinnamon. However, changes in total cholesterol, LDL-C, and triglycerides were positively linked with the duration of supplementation.
