Fenugreek supplementation could be considered as an effective lipid-lowering medicinal plant.
Pooled data of indicated a significant impact of fenugreek supplementation on lowering total cholesterol (TC), low-density lipoprotein (LDL), and triglyceride (TG) and increasing the high-density lipoprotein (HDL) level compared with the control group.
There were no significant differences in TC, TG, and LDL between pre- and post-fenugreek studies in the noncontrolled studies however, the result of combination of four studies without control group showed a significant increase in mean HDL. The results of subgroup analysis showed that the fenugreek reduced the TG and LDL and increases HDL levels in diabetic subjects more effectively.
