A comprehensive insight into effects of green tea extract in polycystic ovary syndrome: a systematic review

Maleki V, Taheri E, Varshosaz P, Tabrizi FPF, Moludi J, Jafari-Vayghan H, Shadnoush M, Jabbari SHY, Seifoleslami M, Alizadeh M · Reproductive Biology and Endocrinology · 2021 September 23

DOI 10.1186/s12958-021-00831-z

Objective

To evaluates the potential roles of green tea extract (GTE) on metabolic variables, hormone levels, and ovarian function in PCOS.

Conclusions

This review suggests that green tea extract (GTE) could be considered a potential agent to attenuate PCOS complications mainly due to its effect on weight loss and glycemic levels.

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Insights

Green tea extract could be considered a potential agent to attenuate PCOS complications mainly due to its effect on weight loss and glycemic levels.

Current evidence indicates that green tea extract (GTE) supplementation has potential beneficial effects on PCOS. Of 314 articles found in the search, four human studies and four animal studies were included. All studies in humans showed the effects of GTE on weight loss. GTE's effect on decreasing testosterone levels in humans and LH levels in animals were also reported. In addition, increases in FSH and progesterone levels in animal models were observed. Although GTE improved fasting blood sugar and insulin levels, the effect of GTE on inflammatory parameters, such as TNF-alpha and IL-6 and antioxidant status, was limited to animal studies.