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2021 Chinese Herbal Medicines
Network Pharmacology Jin Yin Hua
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Chinese Medicine Research Hub
Network Pharmacology
Honeysuckle extract could provoke anaphylaxis and specific ingredients in honeysuckle potentially trigger this reaction.
2021 Chinese Herbal Medicines Anaphylaxis effect and substance basis of honeysuckle extract
Feng Y, Qin G, Jing Z, Wang Y, Zhou Y
Executive Summary
Write an executive summary in the form of a blog article on the topic of "Research into Chinese medicine treatment for Anaphylaxis" summarising the research below and using language that can be easily understood by patients and avoiding medical jargon using a professional and caring tone of voice.
Write an executive summary in the form of a blog article on the topic of "Researched Chinese medicine treatments for Anaphylaxis" summarising the research below in an objective and easy to understand way, and using language that can be easily understood by patients. Group the article into Chinese medicine treatments first, followed by nutrition and other treatments. Avoid using medical jargon and use a professional and caring tone of voice.
Write me a concise but easy to understand executive summary on the topic of "Chinese medicine treatments for Anaphylaxis" based on the following research that I will give you. Your summary should be 2 paragraphs long in Australian English spelling and include references to the studies.
A Network Pharmacology published in 2021 in the journal Chinese Herbal Medicines found that Honeysuckle extract could provoke anaphylaxis and specific ingredients in honeysuckle potentially trigger this reaction. In the methodology, rat peritoneal mast cells were separated and purified, then incubated with a compound, saline, and honeysuckle extract at 37°C for varying time intervals. Cell degranulation was observed under microscopes, and the percentage of Annexin V positive cells, which reflect cell degranulation rate, was detected via flow cytometry. Rats were given honeysuckle extract injections, and afterward, symptoms, histamine, and tryptase levels were analysed to study the anaphylaxis effect.
In the discussion of results, it was discovered that the percentage of Annexin V positive cells and cell degranulation ratio significantly rose in cells treated with honeysuckle extract. Histamine and tryptase levels also increased noticeably after injection of honeysuckle extract. Regression analysis identified certain peaks as potential anaphylactoid ingredients, indicating that honeysuckle could induce anaphylaxis and there were likely specific substances in honeysuckle that caused this reaction.
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