Antitussive

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Chinese Medicine Research Hub

Systematic Review

Honey is effective in treating coughs in children above 12 months.

2022 Cureus Journal of Medical Science Comparing the Effectiveness of Honey Consumption With Anti-Cough Medication in Pediatric Patients: A Systematic Review
Mashat GD, Hazique M, Khan KI, Ramesh P, Kanagalingam S, Ul Haq Z, Victory Srinivasan N, Khan AI, Khan S

Chinese Medicine Research Hub

Review Article

Milk and honey mixture seems to be at least as effective as dextromethorphan and levodropropizine, the most prescribed over-the-counter antitussives in Italy, in non-specific acute cough in children.

2015 Allergologia et Immunopathologia Effect of multiple honey doses on non-specific acute cough in children. An open randomised study and literature review
Miceli Sopo S, Greco M, Monaco S, Varrasi G, Di Lorenzo G, Simeone G

Chinese Medicine Research Hub

Systematic Review

Radish seed has been demonstrated to have beneficial effects on hypertension, obesity, diabetes mellitus, constipation, and cough.

2013 Evidence-Based Complementary and Alternative Medicine A Review of the Phytochemistry and Pharmacological Activities of Raphani Semen
Tung-Ting Sham, Ailsa Chui-Ying Yuen, Yam-Fung NgChi-On ChanDaniel Kam-Wah Mok, and Shun-Wan Chan

Executive Summary

Write an executive summary in the form of a blog article on the topic of "Research into Chinese medicine treatment for Antitussive" summarising the research below and using language that can be easily understood by patients and avoiding medical jargon using a professional and caring tone of voice.

Write an executive summary in the form of a blog article on the topic of "Researched Chinese medicine treatments for Antitussive" summarising the research below in an objective and easy to understand way, and using language that can be easily understood by patients. Group the article into Chinese medicine treatments first, followed by nutrition and other treatments. Avoid using medical jargon and use a professional and caring tone of voice.

Write me a concise but easy to understand executive summary on the topic of "Chinese medicine treatments for Antitussive" based on the following research that I will give you. Your summary should be 2 paragraphs long in Australian English spelling and include references to the studies.

A Systematic Review published in 2022 in the journal Cureus Journal of Medical Science found that Honey is effective in treating coughs in children above 12 months. The researchers undertook a systematic review of literature across five databases, using a Medical Subject Heading strategy, keywords, and defined inclusion and exclusion criteria to identify relevant studies. This review incorporated a range of study types, including systematic reviews, meta-analyses, randomized controlled trials, observational studies and cross-sectional studies. Those articles without a clear methodology section were excluded. The quality of the remaining literature was appraised using a specific checklist. Following the review, it was found that honey is effective in treating coughs in children older than 12 months. Cold and cough medications were also found to be safe, if given at therapeutic doses. However, a note of caution was highlighted for the use of these medications in children under two years, as fatalities have been recorded in some cases; although further studies are recommended to establish a clear safety profile.

A Review Article published in 2015 in the journal Allergologia et Immunopathologia found that Milk and honey mixture seems to be at least as effective as dextromethorphan and levodropropizine, the most prescribed over-the-counter antitussives in Italy, in non-specific acute cough in children. Honey is recommended for non-specific acute paediatric cough by the Australian guidelines. Current available randomised clinical trials evaluated the effects of a single evening dose of honey, but multiple doses outcomes have never been studied. 134 children suffering from non-specific acute cough were randomised to receive for three subsequent evenings a mixture of milk (90 ml) and wildflower honey (10 ml) or a dose of DM or LDP adjusted for the specific age. The effectiveness was evaluated by a cough questionnaire answered by parents. Primary end-point efficacy was therapeutic success. The latter was defined as a decrease in cough questionnaire score greater than 50% after treatment compared with baseline values. Three children were excluded from the study, as their parents did not complete the questionnaire. Therapeutic success was achieved by 80% in the honey and milk group and 87% in OTC medication group (p = 0.25).

A Systematic Review published in 2013 in the journal Evidence-Based Complementary and Alternative Medicine found that Radish seed has been demonstrated to have beneficial effects on hypertension, obesity, diabetes mellitus, constipation, and cough. The dried ripe seed of Raphanus sativus L., commonly known as radish seed (or Raphani Semen), is used as traditional Chinese medicine (TCM) to treat constipation, chronic tracheitis, and hypertension. The major active compounds in Raphani Semen are alkaloids, glucosinolates, brassinosteroids, and flavonoids. Fatty acids are its main nutritional contents. Raphani Semen has been demonstrated to have beneficial effects on hypertension, obesity, diabetes mellitus, constipation, and cough. So far, there is no report about the adverse/toxic effects of this herb on humans. However, Raphani Semen processed by roasting was reported to exhibit some adverse effects on mice. Additionally, erucic acid, the main fatty acid in Raphani Semen, was shown to enhance the toxicity of doxorubicin. Thus, Raphani Semen has a potential risk of causing toxicity and drug interaction. In summary, Raphani Semen is a valuable TCM herb with multiple pharmacological effects. More studies on Raphani Semen could help better understand its pharmacological mechanisms so as to provide clear scientific evidence to explain its traditional uses, to identify its therapeutic potential on other diseases, and to understand its possible harmful effects.

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