Nephrotic Syndrome
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Published research studies are articles that present the findings of original research that has undergone a peer-review process and has been made publicly available in scholarly journals, books or other media.
Potential Molecular Mechanisms of Ephedra Herb in the Treatment of Nephrotic Syndrome Based on Network Pharmacology and Molecular Docking
2022 Jul 05 BioMed Research International Yao T, Wang Q, Han S, Lu Y, Xu Y, Wang Y
The study identified 22 main active ingredients in EH, such as quercetin, kaempferol, luteolin, and naringenin, targeting 105 NS-related genes. The PPI network revealed 53 core targets, including AKT1, TNF, IL6, VEGFA, and IL1B, crucial in NS treatment. Enrichment analysis highlighted pathways like PI3K-Akt signaling, TNF signaling, and AGE-RAGE signaling. Molecular docking confirmed good binding between active ingredients (kaempferol, luteolin, quercetin, naringenin) and target proteins (AKT1, TNF), suggesting potential mechanisms for EH in NS treatment.
Network Pharmacology
Clinical Efficacy of Adjuvant Treatment of Primary Nephrotic Syndrome in Pediatric Patients with Chinese Medicine
2022 Jan 25 Journal of Healthcare Engineering Wu H, Zhang L, Liu Q, Ren B, Li J
Adjuvant treatment of pediatric primary nephrotic syndrome with traditional Chinese medicine could benefit the children.
Clinical Study Children's HealthSign In
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